Chemoproteomics yields a selective molecular host for acetyl-CoA
W. K. Lieberman, Z. A. Brown, Y. Jing, N. D. Evans, I. Jhulki, C. Grose, J. e. Jones, J. L. Meier
The paper develops a chemoproteomics-based method to selectively detect acetyl-CoA using a Nanoluc-NAA50 fusion protein and a ligand displacement assay.
bioRxiv · Dec 19, 2022Biochemistry