Author

C. H. Luk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

J. Enninga· 2 shared A. Rodgers· 1 shared E. Pellegrino· 1 shared H. Morris· 1 shared L. Deriano· 1 shared M. G. Gutierrez· 1 shared N. Athanasiadi· 1 shared R. Morrison· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

J. Enninga

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LRRK2 kinase dependent and independent function on endolysosomal repair promotes macrophage cell death

R. Morrison, S. R. G. Mihaylov, C. H. Luk, A. Rodgers, N. Athanasiadi, H. Morris, E. Pellegrino, S. K. Ultanir, M. G. Gutierrez

This study identifies LRRK2-G2019S-dependent lysosomal membrane repair defects in macrophages leading to increased cell death.

bioRxiv · Sep 27, 2023 · PreprintCell Biology

Salmonella endorses a dormant state within human epithelial cells for persistent infection

C. H. Luk, Y.-y. Chang, J. Enninga

This paper identifies a dormant Salmonella Typhimurium subpopulation in human epithelial cells using a new fluorescent reporter, revealing distinct dormancy regulation compared to macrophages.

PLOS Pathogens · Apr 30, 2021Peer-reviewedMicrobiology

Salmonella subverts autophagy balancing bacterial fate and cellular inflammation

C. H. Luk, W. Yu, L. Deriano, J. Enninga

This study identifies c-MYC as a negative regulator of Salmonella Typhimurium cytosolic lifestyle and shows how LC3 and SopF modulate SCV stability to balance bacterial survival and host inflammation.

bioRxiv · Nov 15, 2020 · PreprintMicrobiology