Author

C. H. Ottensmeier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

P. Vijayanand· 3 shared A. Chawla· 1 shared A. L. R. Premlal· 1 shared A. Madrigal· 1 shared B. J. Schmiedel· 1 shared C. C. Hedrick· 1 shared C. E. Olingy· 1 shared C. Gonzalez-Colin· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersImmunology

P. Vijayanand

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptomes and metabolism define mouse and human MAIT cell heterogeneity

S. Chandra, G. Ascui, T. Riffelmacher, A. Chawla, C. Ramirez-Suastegui, V. C. Castelan, G. Seumois, H. Simon, M. P. Murray, G.-Y. Seo, A. L. R. Premlal, G. Verstichel, Y. Li, C.-H. Lin, J. Greenbaum, , M. Kronenberg

This study identifies MAIT cell heterogeneity in mice and humans through single-cell RNA sequencing and metabolic analysis, revealing distinct transcriptomes and metabolic states in different tissues and species.

bioRxiv · Dec 20, 2021 · PreprintImmunology

COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types.

B. J. Schmiedel, V. Chandra, J. Rocha, C. Gonzalez-Colin, S. Bhattacharyya, A. Madrigal, C. H. Ottensmeier, F. Ay, P. Vijayanand

The paper identifies COVID-19 risk variants associated with gene expression in multiple immune cell types, revealing potential mechanisms linking genetic risk to disease severity.

bioRxiv · Dec 1, 2020Immunology

Interplay of Monocytes and T Lymphocytes in COVID-19 Severity

L. E. Padgett, H. Q. Dinh, S. J. Chee, C. E. Olingy, R. Wu, D. J. Araujo, P. Vijayanand, C. H. Ottensmeier, C. C. Hedrick

The study uses mass cytometry to analyze immune cell subsets in convalescent COVID-19 patients, linking monocyte and T cell populations to disease severity and clinical markers.

bioRxiv · Jul 17, 2020 · PreprintImmunology

Spatially discrete signalling niches regulate fibroblast heterogeneity in human lung cancer

C. J. Hanley, S. Waise, R. Parker, M. A. Lopez, J. Taylor, L. Kimbley, J. West, C. H. Ottensmeier, M. J. Rose-Zerilli, G. J. Thomas

The paper identifies fibroblast subpopulations in lung cancer using single-cell RNA sequencing and shows their spatial distribution and regulation by TGF-β1 and IL-1.

bioRxiv · Jun 8, 2020 · PreprintCancer Biology