Author

C. I. Stoddard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. A. Matsen· 5 shared J. Overbaugh· 5 shared H. Y. Chu· 4 shared K. Sung· 4 shared A. Finzi· 2 shared C. R. Wolf· 2 shared D. A. Lehman· 2 shared D. Wamalwa· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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5 shared papersImmunology

F. A. Matsen

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2

J. Guenthoer, M. E. Garrett, M. Lilly, D. M. Depierreux, F. Ruiz, M. Chi, C. I. Stoddard, V. Chohan, K. Sung, D. Ralph, H. Y. Chu, F. A. Matsen, J. Overbaugh

This paper identifies diverse functional antibodies targeting the S2 subunit of SARS-CoV-2 spike, including one with broad neutralization activity across multiple coronaviruses.

bioRxiv · Feb 26, 2024 · PreprintImmunology

Elevated binding and functional antibody responses to SARS-CoV-2 in infants versus mothers

C. I. Stoddard, K. Sung, Z. A. Yaffe, H. Weight, G. Beaudoin-Bussieres, J. G. Galloway, S. Gantt, J. Adhiambo, E. R. Begnel, E. Ojee, J. Slyker, D. Wamalwa, J. Kinuthia, A. Finzi, F. A. Matsen, , J. Overbaugh

The paper compares SARS-CoV-2 antibody responses between infants and mothers, finding higher binding and functional antibody levels in infants, particularly in the fusion peptide region.

bioRxiv · Feb 6, 2023Immunology

Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection

J. Guenthoer, M. Lilly, T. N. Starr, B. Dadonaite, K. N. Lovendahl, J. T. Croft, C. I. Stoddard, V. Chohan, S. Ding, F. Ruiz, M. S. Kopp, A. Finzi, J. D. Bloom, H. Y. Chu, K. K. Lee, J. Overbaugh

This study identifies four broad, potent monoclonal antibodies against SARS-CoV-2 spike protein that neutralize multiple variants, including Omicron and XBB.1.5, targeting conserved regions with high functional constraint.

bioRxiv · Dec 15, 2022 · PreprintImmunology

Distinct antibody responses to endemic coronaviruses pre- and post-SARS-CoV-2 infection in Kenyan infants and mothers

C. I. Stoddard, K. Sung, E. Ojee, J. Adhiambo, E. R. Begnel, J. Slyker, S. Gantt, F. A. Matsen, J. Kinuthia, D. Wamalwa, J. Overbaugh, D. A. Lehman

This study examines antibody responses to endemic coronaviruses before and after SARS-CoV-2 infection in Kenyan mothers and infants, finding increased eHCoV antibodies in mothers but not infants post-infection.

bioRxiv · Jun 2, 2022Microbiology

High resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies

M. E. Garrett, J. Galloway, H. Y. Chu, H. L. Itell, C. I. Stoddard, C. R. Wolf, J. K. Logue, D. McDonald, F. A. Matsen, J. Overbaugh

This study identifies antibody escape pathways for SARS-CoV-2 spike protein using Phage-DMS, revealing variable escape mutations in immunodominant regions and individual epitope targeting differences.

bioRxiv · Nov 16, 2020Immunology

Epitope profiling reveals binding signatures of SARS-CoV-2 immune response and cross-reactivity with endemic HCoVs

C. I. Stoddard, J. Galloway, H. Y. Chu, M. M. Shipley, H. L. Itell, C. R. Wolf, J. K. Logue, A. Magedson, K. Sung, M. Garrett, K. H. Crawford, U. Laserson, F. A. Matsen, Julie Overbaugh

This study maps SARS-CoV-2 antibody epitopes and identifies cross-reactive sequences with endemic HCoVs in COVID-19 patients.

bioRxiv · Oct 29, 2020 · PreprintImmunology