Author

J. K. Logue

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 7 Approach:experimental assay· 6 Organism:human· 6 Research Focus:host-pathogen & immune response· 5 Research Focus:cell type annotation· 3 Approach:deep learning· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. Y. Chu· 8 shared D. Corti· 3 shared D. Veesler· 3 shared F. A. Matsen· 3 shared J. E. Bowen· 3 shared M. E. Garrett· 3 shared A. C. Walls· 2 shared A. Gori· 2 shared

Activity by Year

2020-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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8 shared papersImmunology

H. Y. Chu

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines

J. E. Bowen, K. R. Sprouse, A. C. Walls, I. G. Mazzitelli, J. K. Logue, N. M. Franko, K. Ahmed, A. Shariq, E. Cameroni, A. Gori, A. Bori, C. M. Posavad, J. M. Dan, Z. Zhang, D. Weiskopf, , D. Veesler

This study evaluates neutralizing activity against Omicron BA.1 and BA.2 variants elicited by various vaccines and finds that booster doses enhance neutralizing titers and breadth across all vaccine platforms.

bioRxiv · Mar 15, 2022 · PreprintImmunology

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

A. J. Greaney, R. T. Eguia, T. N. Starr, K. Khan, N. Franko, J. K. Logue, S. M. Lord, C. Speake, H. Y. Chu, A. Sigal, J. D. Bloom

The paper examines the antibody response to the SARS-CoV-2 Delta variant, showing it targets class 1 and 2 epitopes more than class 3, and that mutations in these regions reduce antibody binding.

bioRxiv · Mar 12, 2022Microbiology

SARS-CoV-2 spike conformation determines plasma neutralizing activity

J. E. Bowen, A. C. Walls, A. Joshi, K. R. Sprouse, C. Stewart, M. A. Tortorici, N. M. Franko, J. K. Logue, I. G. Mazzitelli, S. W. Tiles, K. Ahmed, A. Shariq, G. Snell, N. T. Iqbal, J. Geffner, , D. Veesler

This study shows that vaccines encoding a prefusion-stabilized SARS-CoV-2 spike protein induce higher neutralizing antibody titers and better variant cross-neutralization compared to other vaccines or infection.

bioRxiv · Dec 19, 2021 · PreprintImmunology

Macaque-human differences in SARS-CoV-2 Spike antibody response elicited by vaccination or infection

A. Willcox, K. Sung, M. E. Garrett, J. G. Galloway, M. A. OConnor, J. H. Erasmus, J. K. Logue, D. W. Hawman, H. Y. Chu, K. J. Hasenkrug, D. H. Fuller, F. A. Matsen, J. Overbaugh

This study compares SARS-CoV-2 Spike antibody responses between macaques and humans after vaccination or infection, identifying shared and distinct epitope recognition patterns and escape pathways.

bioRxiv · Dec 1, 2021 · PreprintImmunology

A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy

A. J. Greaney, T. N. Starr, R. T. Eguia, A. N. Loes, K. Khan, F. Karim, S. Cele, J. E. Bowen, J. K. Logue, D. Corti, D. Veesler, H. Y. Chu, A. Sigal, J. D. Bloom

This study compares antibody responses to early SARS-CoV-2 isolates and the B.1.351 variant, finding shifts in immunodominance hierarchy within the spike receptor-binding domain.

bioRxiv · Oct 12, 2021Microbiology

Comprehensive characterization of the antibody responses to SARS-CoV-2 Spike protein after infection and/or vaccination

M. E. Garrett, J. G. Galloway, C. Wolf, J. K. Logue, N. Franko, H. Y. Chu, F. Matsen, J. M. Overbaugh

This study characterizes antibody responses to SARS-CoV-2 Spike protein after infection and vaccination, identifying epitope binding patterns and escape mutation profiles.

bioRxiv · Oct 5, 2021Immunology

High resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies

M. E. Garrett, J. Galloway, H. Y. Chu, H. L. Itell, C. I. Stoddard, C. R. Wolf, J. K. Logue, D. McDonald, F. A. Matsen, J. Overbaugh

This study identifies antibody escape pathways for SARS-CoV-2 spike protein using Phage-DMS, revealing variable escape mutations in immunodominant regions and individual epitope targeting differences.

bioRxiv · Nov 16, 2020Immunology

Epitope profiling reveals binding signatures of SARS-CoV-2 immune response and cross-reactivity with endemic HCoVs

C. I. Stoddard, J. Galloway, H. Y. Chu, M. M. Shipley, H. L. Itell, C. R. Wolf, J. K. Logue, A. Magedson, K. Sung, M. Garrett, K. H. Crawford, U. Laserson, F. A. Matsen, Julie Overbaugh

This study maps SARS-CoV-2 antibody epitopes and identifies cross-reactive sequences with endemic HCoVs in COVID-19 patients.

bioRxiv · Oct 29, 2020 · PreprintImmunology