Author

N. Socci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Blackford· 1 shared A. Eisenberg· 1 shared A. Hayashi· 1 shared A. Henssen· 1 shared A. Heyde· 1 shared A. Kentsis· 1 shared A. P. Makohon-Moore· 1 shared A. Penson· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Blackford

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3 papers

Recent·Most cited

Dual inhibition of SHP2 and autophagy suppresses NF1-associated Malignant Peripheral Nerve Sheath Tumors

S. Farouk Sait, K.-h. Tang, S. Angus, R. Brown, D. Sun, X. Xie, C. Iltis, M. Lien, N. Socci, T. Bale, C. Davis, S. A. H. Dixon, C. Zhang, D. W. Clapp, B. G. Neel, L. F. Parada

This study shows that combining SHP2 and autophagy inhibition effectively suppresses NF1-associated MPNSTs in mouse models, suggesting a potential new treatment approach.

bioRxiv · Aug 18, 2022 · PreprintCancer Biology

Evolutionary Origins of Recurrent Pancreatic Cancer

H. Sakamoto, M. Attiyeh, J. Gerold, A. P. Makohon-Moore, A. Hayashi, J. Hong, R. Kappagantula, L. Zhang, J. Melchor, J. Reiter, A. Heyde, C. Bielski, A. Penson, D. Chakravarty, E. O'Reilly, , C. A. Iacobuzio-Donahue

This study identifies genetic features of recurrent pancreatic cancer through sequencing and finds that treatment-induced genetic changes and potential second primary tumors influence recurrence.

bioRxiv · Oct 31, 2019Cancer Biology

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

A. Henssen, R. Koche, J. Zhuang, E. Jiang, C. Reed, A. Eisenberg, E. Still, I. MacArthur, E. Rodriguez-Fos, S. Gonzalez, M. Puiggros, A. Blackford, C. Mason, E. De Stanchina, M. Gonen, , A. Kentsis

This study identifies PGBD5 as an oncogenic DNA transposase in rhabdoid tumors, causing site-specific genomic rearrangements through PSS sequences and end-joining repair.

bioRxiv · Feb 23, 2017Cancer Biology