Author

C. J. Giuliano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. Lourido· 3 shared B. S. Waldman· 2 shared C. A. Hunter· 2 shared A. A. Koshy· 1 shared A. C. Palladino· 1 shared A. G. Sanderlin· 1 shared A. L. Herneisen· 1 shared A. Lin· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersMicrobiology

S. Lourido

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The latent stage of Toxoplasma gondii is targeted by the immune response and host protective

L. A. Shallberg, J. N. Eberhard, A. Winn, S. Chandrasekaran, C. J. Giuliano, E. F. Merritt, E. Willis, D. A. Christian, D. L. Aldridge, M. Bunkofske, M. Jacquet, F. Dzierszinski, E. Katifori, S. Lourido, A. A. Koshy, C. A. Hunter

This study shows immune pressure targets Toxoplasma gondii bradyzoites, which mitigate tissue damage and promote host-parasite survival.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

Functional profiling of the Toxoplasma genome during acute mouse infection

C. J. Giuliano, K. J. Wei, F. M. Harling, B. S. Waldman, M. A. Farringer, E. A. Boydston, T. C. T. Lan, R. W. Thomas, A. L. Herneisen, A. G. Sanderlin, I. Coppens, J. D. Dvorin, S. Lourido

The paper uses CRISPR screens to identify 300+ genes in Toxoplasma gondii that affect parasite fitness in mice, revealing new roles in host-parasite interactions and potential drug targets.

bioRxiv · Mar 5, 2023 · PreprintMicrobiology

A positive feedback loop controls Toxoplasma chronic differentiation

M. H. Licon, C. J. Giuliano, S. Chakladar, L. Shallberg, B. S. Waldman, C. A. Hunter, S. Lourido

The paper identifies a positive feedback loop between BFD1 and BFD2 that drives Toxoplasma gondii chronic differentiation.

bioRxiv · Apr 6, 2022Microbiology

Combining CRISPR/Cas9 mutagenesis and a small-molecule inhibitor to probe the function of MELK in cancer

C. J. Giuliano, A. Lin, J. C. Smith, A. C. Palladino, J. M. Sheltzer

This study uses CRISPR/Cas9 and a MELK inhibitor to show that MELK knockout cancer cells grow normally, suggesting anti-MELK therapies may not be effective as monotherapies.

bioRxiv · Oct 16, 2017Cancer Biology