Author

B. S. Waldman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Lourido· 4 shared C. J. Giuliano· 2 shared A. G. Sanderlin· 1 shared A. K. Shalek· 1 shared A. L. Herneisen· 1 shared A. Ono· 1 shared A.-L. E. Lawrence· 1 shared C. A. Hunter· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersMicrobiology

S. Lourido

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Author profile →

4 papers

Recent·Most cited

Functional profiling of the Toxoplasma genome during acute mouse infection

C. J. Giuliano, K. J. Wei, F. M. Harling, B. S. Waldman, M. A. Farringer, E. A. Boydston, T. C. T. Lan, R. W. Thomas, A. L. Herneisen, A. G. Sanderlin, I. Coppens, J. D. Dvorin, S. Lourido

The paper uses CRISPR screens to identify 300+ genes in Toxoplasma gondii that affect parasite fitness in mice, revealing new roles in host-parasite interactions and potential drug targets.

bioRxiv · Mar 5, 2023 · PreprintMicrobiology

A positive feedback loop controls Toxoplasma chronic differentiation

M. H. Licon, C. J. Giuliano, S. Chakladar, L. Shallberg, B. S. Waldman, C. A. Hunter, S. Lourido

The paper identifies a positive feedback loop between BFD1 and BFD2 that drives Toxoplasma gondii chronic differentiation.

bioRxiv · Apr 6, 2022Microbiology

Toxoplasma gondii subverts the host ESCRT machinery for parasite uptake of host cytosolic proteins

Y. Rivera-Cuevas, J. Mayoral, M. Di Cristina, A.-L. E. Lawrence, E. B. Olafsson, D. Thornhill, B. S. Waldman, A. Ono, J. Sexton, S. Lourido, L. M. Weiss, V. B. Carruthers

This study identifies TgGRA14 as a parasite protein that recruits the host ESCRT machinery to facilitate uptake of host cytosolic proteins across the parasitophorous vacuole membrane.

bioRxiv · Jul 21, 2021Microbiology

Identification of a master regulator of differentiation in Toxoplasma

B. S. Waldman, D. Schwarz, M. H. Wadsworth, J. P. J. Saeij, A. K. Shalek, S. Lourido

This study identifies BFD1 as a master regulator of differentiation in Toxoplasma gondii through genetic screening and single-cell profiling, showing its necessity and sufficiency for the transition from tachyzoites to bradyzoites.

bioRxiv · Jun 5, 2019Microbiology