Author

A. L. Herneisen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Lourido· 4 shared A. W. Chan· 2 shared E. Shortt· 2 shared A. G. Sanderlin· 1 shared B. S. Waldman· 1 shared C. J. Giuliano· 1 shared E. A. Boydston· 1 shared E. Andree· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersMicrobiology

S. Lourido

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle

A. L. Herneisen, M. L. Peters, T. A. Smith, E. Shortt, S. Lourido

This study shows SPARK regulates PKA and PKG stability in Toxoplasma gondii, affecting its asexual cycle transitions.

bioRxiv · Oct 30, 2023Microbiology

Functional profiling of the Toxoplasma genome during acute mouse infection

C. J. Giuliano, K. J. Wei, F. M. Harling, B. S. Waldman, M. A. Farringer, E. A. Boydston, T. C. T. Lan, R. W. Thomas, A. L. Herneisen, A. G. Sanderlin, I. Coppens, J. D. Dvorin, S. Lourido

The paper uses CRISPR screens to identify 300+ genes in Toxoplasma gondii that affect parasite fitness in mice, revealing new roles in host-parasite interactions and potential drug targets.

bioRxiv · Mar 5, 2023 · PreprintMicrobiology

Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

A. W. Chan, M. Broncel, E. Yifrach, N. R. Haseley, S. Chakladar, E. Andree, A. L. Herneisen, E. Shortt, M. Treeck, S. Lourido

This study identifies CDPK1 targets in Toxoplasma gondii, revealing a trafficking adaptor complex that regulates microneme exocytosis and host cell invasion.

bioRxiv · Jan 11, 2023 · PreprintMicrobiology

De novo mapping of the apicomplexan Ca2+-responsive proteome

A. L. Herneisen, Z.-H. Li, A. W. Chan, S. N. Moreno, S. Lourido

The paper maps the Ca2+-responsive proteome of T. gondii using phosphoproteomics and thermal proteome profiling, identifying both known and novel proteins involved in Ca2+ signaling pathways.

bioRxiv · May 25, 2022 · PreprintMicrobiology