Author

C. L. Linster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

N. Paczia· 2 shared A. Baron· 1 shared C. Capelle· 1 shared C. Guerin· 1 shared C. Leonard· 1 shared C. Zhu· 1 shared D. Brenner· 1 shared D. Coowar· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

N. Paczia

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis

E. Danileviciute, N. Zeng, C. Capelle, N. Paczia, M. A. Gillespie, H. Kurniawan, D. Coowar, D. Vogt-Weisenhorn, G. Gomez-Giro, M. Grusdat, A. Baron, C. Guerin, D. G. Franchina, C. Leonard, O. Domingues, , F. Q. He

This study shows PARK7/DJ-1 enhances PDH activity in Tregs by inhibiting PDHA phosphorylation, maintaining Treg homeostasis and reducing EAE severity.

bioRxiv · Dec 20, 2019Biochemistry

NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells

J. Becker-Kettern, N. Paczia, J.-F. Conrotte, C. Zhu, O. Fiehn, P. P. Jung, L. M. Steinmetz, C. L. Linster

This study shows that NAD(P)HX repair deficiency in yeast and human cells causes metabolic perturbations, including NADHX accumulation, NAD+ depletion, and impaired mitochondrial function.

bioRxiv · Jul 5, 2018Biochemistry