Author

C. L. Piazza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:structural biology· 2 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

N. J. Mantis· 3 shared B. Muriuki· 2 shared D. D. Weis· 2 shared D. J. Vance· 2 shared H. M. E. Haque· 2 shared L. A. Cavacini· 2 shared M. J. Rudolph· 2 shared C. B. Shoemaker· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

N. J. Mantis

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Author profile →

3 papers

Recent·Most cited

Structure of a human monoclonal antibody in complex with Outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi

M. Rudolph, Y. Chen, C. Vorauer, D. Vance, C. L. Piazza, G. G. Willsey, K. McCarthy, B. Muriuki, L. Cavacini, M. Guttman, N. J. Mantis

This study determines the structure of a human monoclonal antibody in complex with OspC from Borreliella burgdorferi, revealing its epitope and interaction mechanism.

bioRxiv · Apr 29, 2024Immunology

Single-domain antibodies reveal unique borreliacidal epitopes on the Lyme disease vaccine antigen, Outer surface protein A (OspA)

D. J. Vance, S. Basir, C. L. Piazza, G. Willsey, H. M. E. Haque, J. M. Tremblay, M. J. Rudolph, B. Muriuki, L. A. Cavacini, D. D. Weis, C. B. Shoemaker, N. J. Mantis

The paper identifies unique borreliacidal epitopes on OspA using VHHs and evaluates their reactivity across OspA serotypes.

bioRxiv · Jan 23, 2024 · PreprintImmunology

Structural Elucidation of a Protective B cell Epitope on Outer Surface Protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi

M. J. Rudolph, S. Davis, H. M. E. Haque, D. D. Weis, D. J. Vance, C. L. Piazza, M. Ejemel, L. A. Cavacini, Y. Wang, L. Mbow, R. D. Gilmore, N. J. Mantis

This paper determines the crystal structure of a protective B cell epitope on OspC, revealing its quaternary nature and informing vaccine design for Lyme disease.

bioRxiv · Nov 28, 2022 · PreprintImmunology