A refined human linear B cell epitope map of Outer surface protein C (OspC) from the Lyme disease spirochete, Borreliella burgdorferi
G. Freeman-Gallant, K. McCarthy, J. L. Yates, K. E. Kulas, M. J. Rudolph, D. J. Vance, N. J. Mantis
The paper evaluates IgG reactivity to OspC-derived peptides in Lyme disease serum samples, identifying C10 as the most reactive epitope and highlighting complexities in B cell responses.
bioRxiv · May 29, 2024 · PreprintImmunology