Author

L. Cavacini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Casadevall· 1 shared A. Wallace· 1 shared B. D. Bryson· 1 shared B. Muriuki· 1 shared C. L. Piazza· 1 shared C. Vorauer· 1 shared D. Vance· 1 shared D. Wisheart· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperImmunology

A. Casadevall

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure of a human monoclonal antibody in complex with Outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi

M. Rudolph, Y. Chen, C. Vorauer, D. Vance, C. L. Piazza, G. G. Willsey, K. McCarthy, B. Muriuki, L. Cavacini, M. Guttman, N. J. Mantis

This study determines the structure of a human monoclonal antibody in complex with OspC from Borreliella burgdorferi, revealing its epitope and interaction mechanism.

bioRxiv · Apr 29, 2024Immunology

Fc-engineered antibodies leverage neutrophils to drive control of Mycobacterium tuberculosis

E. B. Irvine, J. M. Peters, R. Lu, P. S. Grace, J. Sixsmith, A. Wallace, M. Schneider, S. Shin, W. Karpinski, J. C. Hsiao, E. van Woudenbergh, A. Casadevall, B. D. Bryson, L. Cavacini, G. Alter, S. M. Fortune

This study uses Fc-engineered antibodies to enhance Mtb control by leveraging neutrophils, showing restrictive Fc variants improve neutrophil survival and antimicrobial activity in a human whole blood model.

bioRxiv · May 1, 2022 · PreprintImmunology

Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis Against Enterotoxigenic Escherichia coli Infection

S. Giuntini, M. Stoppato, M. Sedic, M. Ejemel, J. R. Pondish, D. Wisheart, Z. A. Schiller, W. D. Thomas, E. Barry, L. Cavacini, M. Klempner, Y. Wang

This study identifies human monoclonal antibodies against CfaE that inhibit ETEC colonization and reduce intestinal colonization in mice.

bioRxiv · May 11, 2018Microbiology