Author

J. Chandanani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

E. A. Campbell· 2 shared P. D. B. Olinares· 2 shared S. A. Darst· 2 shared A. Banerjee· 1 shared B. Chait· 1 shared B. T. Chait· 1 shared C. Aicart-Ramos· 1 shared C. M. Thomas· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

E. A. Campbell

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Author profile →

2 papers

Recent·Most cited

Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing

T. C. McLean, F. Balaguer-Perez, J. Chandanani, C. M. Thomas, C. Aicart-Ramos, S. Burick, P. D. B. Olinares, G. Gobbato, J. E. A. Mundy, B. T. Chait, D. M. Lawson, S. A. Darst, E. A. Campbell, F. Moreno-Herrero, T. B. K. Le

The paper shows that KorB, a DNA-sliding clamp, switches to a repressor role with KorA to mediate long-range gene silencing on plasmid RK2.

bioRxiv · Feb 16, 2024 · PreprintMicrobiology

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain

G. I. Small, O. Federova, P. D. B. Olinares, J. Chandanani, A. Banerjee, Y. J. Choi, H. Molina, B. Chait, S. A. Darst, E. A. Campbell

This study determines cryo-EM structures of SARS-CoV-2 NiRAN domain catalytic intermediates, revealing structural mechanisms for NMPylation and deRNAylation/capping, and explaining substrate preference for capping.

bioRxiv · Sep 25, 2023Biophysics