F. Moreno-Herrero

Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing

The paper shows that KorB, a DNA-sliding clamp, switches to a repressor role with KorA to mediate long-range gene silencing on plasmid RK2.

DNA binding and bridging by human CtIP in the healthy and diseased states

This study investigates the DNA binding and bridging activities of CtIP in healthy and diseased states, identifying a C-terminal DNA-binding domain and showing that tetramerization is required for DNA bridging.

Cytidine triphosphate promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional spreading from parS

The paper investigates how CTP binding enhances ParB-dependent DNA condensation through one-dimensional spreading from parS sites.

Double-stranded RNA bending by AU-tract sequences

The paper identifies AU-tracts in dsRNA that cause structural bending through molecular dynamics simulations and AFM experiments.

Understanding the paradoxical mechanical response of in-phase A-tracts at different force regimes

This study investigates the mechanical behavior of A-tracts across different force regimes using single-molecule experiments and polymer models, revealing intrinsic bending and unusual stiffness.

Bulk and single-molecule analysis of a novel DNA2-like helicase-nuclease reveals a single-stranded DNA looping motor

This study characterizes a bacterial DNA2-like helicase-nuclease, Bad, revealing its ssDNA looping motor activity and cryptic DNA unwinding properties.

Human CtIP forms a tetrameric dumbbell-shaped particle which binds and bridges complex DNA end structures for double-strand break repair

This study shows human CtIP forms a tetramer that binds and bridges DNA ends, facilitating resection for double-strand break repair.

DNA crookedness regulates DNA mechanical properties at short length scales

The paper quantifies DNA crookedness and shows it correlates with DNA stiffness, linking sequence structure to mechanical properties and gene expression.

The C-Terminal Domain Of ParB Is Critical For Dynamic DNA Binding And Bridging Interactions Which Condense The Bacterial Centromere

This study identifies the C-terminal domain of ParB as critical for DNA binding and bridging interactions that drive bacterial chromosome condensation.