Author

C. M. Worthington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

J. E. Pak· 2 shared A. S. Puschnik· 1 shared B. Castillo-Rojas· 1 shared C. M. Warnes· 1 shared C. Y. Chiu· 1 shared D. R. Glasner· 1 shared D. R. Sandoval· 1 shared E. Harris· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

J. E. Pak

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2 papers

Recent·Most cited

Open-source milligram-scale, four channel, automated protein purification system

R. R. Puccinelli, S. S. Sama, C. M. Worthington, A. S. Puschnik, J. E. Pak, R. Gomez-Sjoberg

The paper describes an open-source automated protein purification system capable of parallelizing milligram-scale purification of multiple recombinant proteins.

bioRxiv · Aug 9, 2023Bioengineering

SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling

S. B. Biering, F. Tramontini Gomes de Sousa, L. V. Tjang, F. Pahmeier, R. Ruan, S. F. Blanc, T. S. Patel, C. M. Worthington, D. R. Glasner, B. Castillo-Rojas, V. Servellita, N. T. Lo, M. P. Wong, C. M. Warnes, D. R. Sandoval, , E. Harris

This study shows SARS-CoV-2 Spike protein causes barrier dysfunction and vascular leak through integrins and TGF-β signaling, independent of viral replication and ACE2.

bioRxiv · Dec 10, 2021 · PreprintMicrobiology