Author

F. Pahmeier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

E. Harris· 3 shared S. B. Biering· 3 shared B. Castillo-Rojas· 2 shared M. P. Wong· 2 shared S. F. Blanc· 2 shared A. I. Kuehne· 1 shared A. Ruggieri· 1 shared A. S. Herbert· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

E. Harris

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread

F. Pahmeier, S. R. Monticelli, X. Feng, C. K. Hjorth, A. Wang, A. I. Kuehne, R. R. Bakken, T. G. Batchelor, S. E. Lee, M. Middlecamp, L. Stuart, D. M. Abelson, J. S. McLellan, S. B. Biering, A. S. Herbert, , E. Harris

This study identifies GP38 as a viral toxin causing vascular leak and shows that specific GP38-targeting antibodies block this effect in vitro and in vivo.

bioRxiv · May 23, 2024Microbiology

The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection

M. P. Wong, E. Y. Juan, S. S. Chelluri, P. Wang, F. Pahmeier, B. Castillo-Rojas, S. F. Blanc, S. B. Biering, R. E. Vance, E. Harris

This study shows DENV NS1 activates inflammasomes in macrophages, leading to IL-1β release without pyroptosis, and that this pathway is protective against DENV infection.

bioRxiv · Sep 21, 2023Immunology

SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling

S. B. Biering, F. Tramontini Gomes de Sousa, L. V. Tjang, F. Pahmeier, R. Ruan, S. F. Blanc, T. S. Patel, C. M. Worthington, D. R. Glasner, B. Castillo-Rojas, V. Servellita, N. T. Lo, M. P. Wong, C. M. Warnes, D. R. Sandoval, , E. Harris

This study shows SARS-CoV-2 Spike protein causes barrier dysfunction and vascular leak through integrins and TGF-β signaling, independent of viral replication and ACE2.

bioRxiv · Dec 10, 2021 · PreprintMicrobiology

A versatile reporter system to monitor virus infected cells and its application to dengue virus and SARS-CoV-2

F. Pahmeier, C. J. Neufeldt, B. Cerikan, V. Prasad, C. Pape, V. Laketa, A. Ruggieri, R. Bartenschlager, M. Cortese

This paper introduces a versatile reporter system that detects virus-infected cells by using protease activity and applies it to dengue virus and SARS-CoV-2.

bioRxiv · Aug 31, 2020Microbiology