Author

C. Madru

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Assay:cryo-EM· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Assay:structural biology· 1

Frequent Co-Authors

L. Sauguet· 2 shared M. Delarue· 2 shared A. C. Alberti· 1 shared A. Haouz· 1 shared B. Raynal· 1 shared D. Flament· 1 shared E. Lindahl· 1 shared G. Pehau-Arnaudet· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

L. Sauguet

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

DNA-binding mechanism and evolution of Replication Protein A

C. Madru, M. Martinez-Carranza, S. Laurent, A. C. Alberti, M. Chevreuil, B. Raynal, A. Haouz, R. A. Le Meur, M. Delarue, D. Flament, M. Krupovic, P. Legrand, L. Sauguet

This study characterizes the DNA-binding mechanism of RPA from Pyrococcus abyssi using crystal and cryo-EM structures, revealing conserved features and a novel archaeal-specific domain.

bioRxiv · Jul 20, 2022Biochemistry

Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA

C. Madru, P. Raia, I. Hugonneau-Beaufet, G. Pehau-Arnaudet, P. England, E. Lindahl, M. Delarue, M. Carroni, L. Sauguet

The paper determines the cryo-EM structure of the PolD-PCNA complex from Pyrococcus abyssi, revealing the molecular basis for increased processivity through PCNA interaction.

bioRxiv · Jan 29, 2020Biochemistry