Author

H. Bolouri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:differential expression· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2

Frequent Co-Authors

J. H. Buckner· 2 shared S. Arora· 2 shared A. Beaubien· 1 shared A. K. Savage· 1 shared A. M. Hocking· 1 shared A. Mungall· 1 shared A. Patel· 1 shared A. S. Gamis· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

J. H. Buckner

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Oncogenic role of a developmentally regulated NTRK2 splice variant

S. S. Pattwell, S. Arora, N. Nuechterlein, M. Zager, K. R. Loeb, P. J. Cimino, N. C. Holland, N. Reche-Ley, H. Bolouri, D. A. A. Bonin, F. Szulzewsky, V. V. Phadnis, T. Ozawa, M. J. Wagner, M. C. Haffner, , E. C. Holland

The paper identifies TrkB.T1, an embryonic NTRK2 splice variant, as an oncogenic driver in multiple tumor types across species, with distinct interactors in developmental and oncogenic pathways.

bioRxiv · Jan 7, 2022 · PreprintCancer Biology

Multimodal Analysis for Human ex vivo Studies Shows Extensive Molecular Changes from Delays in Blood Processing

A. K. Savage, M. V. Gutschow, T. Chiang, K. Henderson, R. Green, M. Chaudhari, E. Swanson, A. T. Heubeck, N. Kondza, K. C. Burley, P. C. Genge, C. Lord, T. Smith, Z. Thomson, A. Beaubien, , T. F. Bumol

This study shows that delayed blood processing causes significant changes in single-cell transcriptomes and plasma proteomes within 6 hours, potentially confounding disease-related biological variance.

bioRxiv · Oct 18, 2020Immunology

The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity

H. Bolouri, C. Speake, D. Skibinski, S. A. Long, A. M. Hocking, D. J. Campbell, J. A. Hamerman, U. Malhotra, J. H. Buckner, BRI COVID-19 Research Team

This study identifies three immune clusters in COVID-19 patients correlated with disease severity and shows that immune responses change dynamically with clinical outcomes.

bioRxiv · Sep 18, 2020Immunology

Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma

H. Feldman, C. Toledo, S. Arora, P. Hoellerbauer, P. Corrin, L. Carter, M. Kufeld, H. Bolouri, R. Basom, J. Delrow, J. McFaline-Figueroa, C. Trapnell, S. Pollard, A. Patel, C. Plaisier, P. Paddison

The paper identifies a quiescent-like state, Neural G0, in human neural stem cells and gliomas using scRNA-seq, linking it to tumor aggressiveness and survival.

bioRxiv · Feb 16, 2020 · PreprintCell Biology

Comprehensive characterization of pediatric AML reveals diverse fusion oncoproteins and age-specific mutational interactions

H. Bolouri, J. E. Farrar, T. J. Triche, R. E. Ries, E. L. Lim, T. A. Alonzo, Y. Ma, R. Moore, A. Mungall, M. A. Marra, J. Zhang, X. Ma, Y. Liu, Y. Liu, J. M. Guidry Auvil, , S. Meshinchi

This study characterizes the molecular landscape of pediatric AML, identifying age-specific mutations and fusion oncoproteins that differ from adult AML.

bioRxiv · Oct 10, 2017Cancer Biology