Author

E. K. Neumann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 5 Organism:human· 4 Assay:imaging· 3 Assay:spatial transcriptomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

J. M. Spraggins· 4 shared J. L. Allen· 3 shared R. M. Caprioli· 3 shared A. B. Fogo· 2 shared E. S. Rivera· 2 shared M. Brewer· 2 shared N. H. Patterson· 2 shared A. R. S. Kruse· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersBiochemistry

J. M. Spraggins

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Author profile →

6 papers

Recent·Most cited

Spatial lipidomics of fresh-frozen spines

K. J. Bender, Y. Wang, C. Y. Zhai, Z. Saenz, A. Wang, E. K. Neumann

This paper develops a method for spatial lipidomics of undecalcified spines using mass spectrometry imaging, revealing lipidomic profiles at 10 micrometer resolution.

bioRxiv · Aug 23, 2023 · PreprintBiochemistry

Resolving the origins of secretory products and anthelmintic responses in a human parasitic nematode at single-cell resolution.

C. R. Henthorn, P. M. Airs, E. K. Neumann, M. Zamanian

This study uses single-cell analysis to identify the cellular origins of secretory products and anthelmintic responses in Brugia malayi microfilariae, revealing cell-specific expression patterns and introducing a cell culture model.

bioRxiv · Aug 30, 2022Microbiology

A Lipid Atlas of the Human Kidney

M. A. Farrow, L. E. M. Tideman, E. K. Neumann, L. G. Migas, N. H. Patterson, M. E. Colley, J. L. Allen, E. L. Pingry, M. Dufresne, H. Yang, M. Brewer, E. S. Rivera, C. E. Romer, K. Djambazova, K. Sharman, , J. M. Spraggins

The paper constructs a spatio-molecular lipid atlas of the human kidney using multimodal imaging and machine learning, revealing lipid profile variations related to sex and BMI.

bioRxiv · Apr 7, 2022Biochemistry

Direct Imaging and Identification of Proteoforms up to 70 kDa from Human Tissue

P. Su, J. P. McGee, K. R. Durbin, M. A. R. Hollas, M. Yang, E. K. Neumann, J. L. Allen, B. S. Drown, F. A. Butun, J. B. Greer, B. P. Early, R. T. Fellers, J. M. Spraggins, J. Laskin, J. M. Camarillo, , N. L. Kelleher

This paper introduces PiMS, a method that detects proteoforms up to 70 kDa in human tissue with high spatial resolution, identifying key metabolic enzymes in kidney tissue.

bioRxiv · Dec 7, 2021 · PreprintBiochemistry

High Spatial Resolution MALDI Imaging Mass Spectrometry ofFresh-Frozen Bone

C. J. Good, E. K. Neumann, C. E. Butrico, J. E. Cassat, R. M. Caprioli, J. M. Spraggins

This study advances MALDI IMS techniques for fresh-frozen murine femurs, revealing lipid distributions linked to specific tissue structures and cell types.

bioRxiv · Oct 1, 2021Biochemistry

Highly Multiplexed Immunofluorescence of the Human Kidney using Co-Detection by Indexing (CODEX)

E. K. Neumann, E. S. Rivera, N. H. Patterson, J. L. Allen, M. Brewer, M. deCaestecker, A. B. Fogo, R. M. Caprioli, J. M. Spraggins

This paper applies CODEX multiplexed immunofluorescence to visualize 23 antigens in human kidney tissue, identifying major cell types and substructures with high resolution.

bioRxiv · Dec 4, 2020Cell Biology