Author

C. R. Rose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

A. A. Lee· 1 shared A. Balesano· 1 shared A. Behzadi· 1 shared A. Ephron· 1 shared A. Mirsaidi· 1 shared A. Muotri· 1 shared A. Ramani· 1 shared A. S. Kalgutkar· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. A. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

M. R. Garnsey, M. C. Robinson, L. T. Nguyen, R. Cardin, J. Tillotson, E. Mashalidis, Y. Aijia, L. Aschenbrenner, A. Balesano, A. Behzadi, B. Boras, J. S. Chang, H. Eng, A. Ephron, T. Foley, , A. A. Lee

This study identifies potent SARS-CoV-2 PLpro inhibitors using machine learning, showing efficacy in a mouse model of COVID-19.

bioRxiv · Jan 26, 2024 · PreprintMicrobiology

Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion, and drug screening

A. Ramani, G. Pasquini, N. Gerkau, O. S. Vinchure, E. Gabriel, I. Rothenaigner, S. Lin, N. Altinisk, D. Rathinam, A. Mirsaidi, O. Goureau, L. Ricci-Vitiani, G. Q. d'alessandris, R. Pallini, B. Wollnik, , J. Gopalakrishnan

This study develops a high-throughput method to generate reliable human brain organoids for modeling microcephaly, glioma invasion, and drug screening.

bioRxiv · Oct 29, 2023Cell Biology

Ion dynamics at the energy-deprived tripartite synapse

M. Kalia, H. G. E. Meijer, S. A. van Gils, M. J. A. M. van Putten, C. R. Rose

This paper develops a biophysical model of a glutamatergic synapse to study synaptic failure during energy deprivation, showing that smaller extracellular space fractions increase vulnerability to ischemic damage.

bioRxiv · Mar 19, 2021Biophysics