Author

C. R. Stewart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. M. Rozario· 2 shared C. Cowled· 2 shared C. L. Rootes· 2 shared C. Rootes· 2 shared G. W. Moseley· 2 shared L. Tribolet· 2 shared P. Jansen Van Vuren· 2 shared S. M. Rawlinson· 2 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

A. M. Rozario

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Author profile →

4 papers

Recent·Most cited

Sub-nucleolar trafficking of Hendra virus matrix protein is regulated by ubiquitination and oligomerisation

S. M. Rawlinson, T. Zhao, F. A. Gomez, C. T. David, C. L. Rootes, P. F. Veuglers, A. M. Rozario, C. R. Stewart, T. D. M. Bell, G. W. Moseley

This study identifies ubiquitination and oligomerisation as mechanisms regulating Hendra virus matrix protein trafficking between sub-nucleolar compartments.

bioRxiv · Aug 10, 2023 · PreprintMicrobiology

Ribosome-profiling reveals restricted post transcriptional ex-pression of antiviral cytokines and transcription factors during SARS-CoV-2 infection

M. R. Alexander, A. M. Brice, P. Jansen Van Vuren, C. Rootes, L. Tribolet, C. Cowled, A. G. D. Bean, C. R. Stewart

This study uses ribosome profiling to show that SARS-CoV-2 restricts post-transcriptional expression of antiviral cytokines and transcription factors in human lung cells.

bioRxiv · Mar 3, 2021Microbiology

ILRUN downregulates ACE2 expression and blocks infection of human cells by SARS-CoV-2

L. Tribolet, M. Alexander, A. Brice, P. Jansen Van Vuren, C. Rootes, K. Mara, M. McDonald, K. Bruce, T. Gough, S. Shi, C. Cowled, A. Bean, C. R. Stewart

This study shows that ILRUN inhibits SARS-CoV-2 replication by downregulating ACE2 expression and blocking viral entry into human cells.

bioRxiv · Nov 13, 2020Cell Biology

Viral hijacking of the nucleolar DNA-damage response machinery: a novel mechanism to regulate host cell biology

S. M. Rawlinson, T. Zhao, A. M. Rozario, C. L. Rootes, P. J. McMillan, A. W. Purcell, A. Woon, G. A. Marsh, K. G. Lieu, L.-F. Wang, H. J. Netter, T. D. Bell, C. R. Stewart, G. W. Moseley

The paper identifies a novel viral mechanism that hijacks the nucleolar DNA-damage response pathway by interacting with Treacle to inhibit rRNA biogenesis.

bioRxiv · Nov 17, 2017Microbiology