Author

G. W. Moseley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:host-pathogen & immune response· 4 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

A. M. Rozario· 2 shared A. R. Harrison· 2 shared C. L. Rootes· 2 shared C. R. Stewart· 2 shared G. A. Marsh· 2 shared S. M. Rawlinson· 2 shared T. Zhao· 2 shared A. W. Purcell· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

A. M. Rozario

Mutual co-authors in cluster

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5 papers

Recent·Most cited

Sub-nucleolar trafficking of Hendra virus matrix protein is regulated by ubiquitination and oligomerisation

S. M. Rawlinson, T. Zhao, F. A. Gomez, C. T. David, C. L. Rootes, P. F. Veuglers, A. M. Rozario, C. R. Stewart, T. D. M. Bell, G. W. Moseley

This study identifies ubiquitination and oligomerisation as mechanisms regulating Hendra virus matrix protein trafficking between sub-nucleolar compartments.

bioRxiv · Aug 10, 2023 · PreprintMicrobiology

Mammalian cells internalize bacteriophages and utilize them as a food source to enhance cellular growth and survival

M. C. Bichet, J. Adderley, L. Avellaneda-Franco, L. J. Gearing, C. Deffrasnes, C. David, G. Pepin, M. P. Gantier, R. C. Lin, R. Patwa, G. W. Moseley, C. Doerig, J. J. Barr

This study shows mammalian cells internalize bacteriophage T4, which enhances cellular growth and survival through AKT-dependent pathways and G1 phase prolongation without triggering inflammatory responses.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology

The Ebola virus interferon antagonist VP24 undergoes active nucleocytoplasmic trafficking

A. R. Harrison, G. W. Moseley

This study identifies the nucleocytoplasmic trafficking mechanisms of the Ebola virus VP24 protein, revealing its CRM1-dependent nuclear export sequence and dual role in immune evasion and replication.

bioRxiv · Aug 10, 2020Microbiology

Antagonism of STAT3 signalling by Ebola virus

A. R. Harrison, M. Dearnley, S. Todd, D. Green, G. A. Marsh, G. W. Moseley

This study identifies how Ebola virus inhibits STAT3 signaling via VP24, using two distinct mechanisms for STAT3 heterodimers and homodimers.

bioRxiv · Aug 10, 2020Microbiology

Viral hijacking of the nucleolar DNA-damage response machinery: a novel mechanism to regulate host cell biology

S. M. Rawlinson, T. Zhao, A. M. Rozario, C. L. Rootes, P. J. McMillan, A. W. Purcell, A. Woon, G. A. Marsh, K. G. Lieu, L.-F. Wang, H. J. Netter, T. D. Bell, C. R. Stewart, G. W. Moseley

The paper identifies a novel viral mechanism that hijacks the nucleolar DNA-damage response pathway by interacting with Treacle to inhibit rRNA biogenesis.

bioRxiv · Nov 17, 2017Microbiology