Author

H. Tillman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Abdolvahabi· 1 shared A. Abu-Zaid· 1 shared A. AlTahan· 1 shared A. Davidoff· 1 shared A. Freiwan· 1 shared A. G. Patel· 1 shared A. Karlstrom· 1 shared A. Pappo· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Abdolvahabi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Diet-induced obesity impacts influenza disease severity and transmission dynamics in ferrets

V. A. Meliopoulos, R. Honce, B. Livingston, V. Hargest, P. Freiden, L. Lazure, P. H. Brigleb, E. A. Karlsson, H. Tillman, E. K. Allen, D. Boyd, P. Thomas, S. Schultz-Cherry

This study shows diet-induced obesity in ferrets increases influenza disease severity and transmission due to altered lung microenvironment and reduced antiviral responses.

bioRxiv · Sep 26, 2023 · PreprintMicrobiology

The Myogenesis Program Drives Clonal Selection and Drug Resistance in Rhabdomyosarcoma

A. G. Patel, X. Chen, X. Huang, M. R. Clay, N. Komarova, M. J. Krasin, A. Pappo, H. Tillman, B. A. Orr, J. McEvoy, B. Gordon, K. Blankenship, C. Reilly, X. Zhou, J. L. Norrie, , M. A. Dyer

This study shows that targeting developmental states in rhabdomyosarcoma can prevent disease recurrence by eliminating myoblast-like cells and inhibiting EGFR-dependent paraxial mesoderm populations.

bioRxiv · Jun 16, 2021Cancer Biology

Geldanamycin inhibits Jumonji histone lysine demethylase KDM4 and targets chimeric transcription factor PAX3-FOXO1

A. Abu-Zaid, S. Singh, W. LIN, J. Low, A. Abdolvahabi, B. Bailey Cooke, J. Bowling, S. Vaithiyalingam, J. Fang, D. Currier, M.-K. Yun, A. AlTahan, D. Fernando, J. Maier, H. Tillman, , J. YANG

This study identifies geldanamycin and its analog 17-DMAG as dual KDM/Hsp90 inhibitors effective against PAX3-FOXO1-driven rhabdomyosarcoma.

bioRxiv · Dec 11, 2019 · PreprintCancer Biology

Unc 51-like autophagy-activating kinase (ULK1) mediates clearance of free {alpha}-globin in {beta}-thalassemia

C. M. Lechauve, J. Keith, E. Khandros, S. Fowler, K. Mayberry, A. Freiwan, C. S. Thom, P. Delbini, E. Boada Romero, J. Zhang, I. Motta, H. Tillman, M. D. Cappellini, M. Kundu, M. J. Weiss

Rapamycin alleviates β-thalassemia by stimulating ULK1-dependent autophagy of toxic free α-globin.

bioRxiv · Oct 26, 2018 · PreprintCell Biology