Author

C. W. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:behavioral assay· 1 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Doherty· 1 shared A. J. Silva· 1 shared A. P. Bracken· 1 shared A. P. Wiita· 1 shared A. Vanderlinden Dibekeme· 1 shared A. Vogt· 1 shared B. Chen· 1 shared C. Hong· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Doherty

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Specific cPRC1 complexes are co-opted to mediate oncogenic gene repression in diffuse midline glioma

D. Gannon, E. Lagan, A. J. Silva, P. Bibawi, A. Doherty, D. Nimmo, R. McCole, C. Monger, G. Genesi, A. Vanderlinden Dibekeme, J. Innes, L. Yang, B. Chen, G. van Mierlo, P. W. Jansen, , G. Brien

The paper identifies specific cPRC1 complexes, CBX4/PCGF4, that mediate oncogenic gene repression in DMG cells downstream of H3K27M mutation.

bioRxiv · Dec 2, 2023Cancer Biology

Optimizing touchscreen measures of rodent cognition by eliminating image bias

J. A. Belarde, C. W. Chen, E. Rafikian, M. Yang, C. M. Troy

This study identifies and corrects image bias in a touchscreen cognitive task for rodents, improving the accuracy of cognitive assessments by using more similar image pairings.

bioRxiv · Apr 5, 2021 · PreprintAnimal Behavior & Cognition

Signaling input from divergent pathways subverts malignant B-cell transformation

L. N. Chan, M. A. Murakami, M. E. Robinson, R. Caeser, T. Sadras, J. Lee, K. N. Cosgun, K. Kume, V. Khairnar, G. Xiao, M. Ahmed, E. Aghania, G. Deb, C. Hurtz, S. Shojaee, , M. Muschen

This study shows that malignant B-cell transformation requires convergence on a single oncogenic pathway, while divergent pathways can subvert transformation and are targets for new therapeutic strategies.

bioRxiv · Mar 12, 2020Cancer Biology