Author

C.-H. G. Lucas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:CITE-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. Ashworth· 1 shared A. B. Heimberger· 1 shared A. Balan· 1 shared A. Bhaduri· 1 shared A. Boire· 1 shared A. Choudhury· 1 shared A. Perry· 1 shared A. Stortchevoi· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Ashworth

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Author profile →

2 papers

Recent·Most cited

A generative reference grammar of healthy TCR repertoires reveals cancer-associated immune remodeling

A. Balan, Y. Elhanati, K. E. Meza Landeros, M. De Almeida Mendes, J. Lai, S. S. A. Zaidi, M. Unal, B. Y. S. Kim, C.-H. G. Lucas, E. Runco, V. K. Puduvalli, J. Gantchev, C. A. Whittaker, P. Sharma, V. Tabar, , R. Karchin

CRAFT, a transformer model, learns a generative grammar of healthy TCR repertoires to detect cancer-associated immune remodeling through structured deviations in sequence space.

bioRxiv · Jun 20, 2026 · PreprintCancer Biology

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

A. Choudhury, M. A. Cady, C.-H. G. Lucas, H. Najem, J. J. Phillips, B. Palikuqi, N. Zakimi, T. Joseph, J. O. Birreuta, W. C. Chen, N. A. O. Bush, S. L. Hervey-Jumper, O. D. Klein, C. M. Toedebusch, C. M. Horbinski, , D. R. Raleigh

This study identifies NOTCH3 as a driver of meningioma tumorigenesis and radiotherapy resistance, showing its role in tumor growth and survival in preclinical models.

bioRxiv · Jul 10, 2023 · PreprintCancer Biology