Author

T. Joseph

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Ashworth· 1 shared A. B. Heimberger· 1 shared A. Bhaduri· 1 shared A. Choudhury· 1 shared A. Perry· 1 shared B. Meethale Mangalassery· 1 shared B. Palikuqi· 1 shared B. Varma· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Ashworth

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α

S. Wang, K. S. Awad, L.-Y. Chen, M. A. H. Siddique, G. A. Ferreyra, C. L. Wang, T. Joseph, Z.-X. Yu, K. Takeda, C. Y. Demirkale, Y. Zhao, J. M. Elinoff, R. L. Danner

bioRxiv · Feb 1, 2024Cell Biology

Size dependent steady-state saturation limit in biomolecular transport through nuclear membranes

S. Padinhare kandiyil, B. Meethale Mangalassery, H. J, T. Joseph, N. Patincharath, G. K. Varier

The paper investigates nuclear transport of dextran molecules below the passive permeability limit and finds that steady-state concentrations inside the nucleus are lower than outside, indicating active regulation.

bioRxiv · Aug 2, 2023Biophysics

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

A. Choudhury, M. A. Cady, C.-H. G. Lucas, H. Najem, J. J. Phillips, B. Palikuqi, N. Zakimi, T. Joseph, J. O. Birreuta, W. C. Chen, N. A. O. Bush, S. L. Hervey-Jumper, O. D. Klein, C. M. Toedebusch, C. M. Horbinski, , D. R. Raleigh

This study identifies NOTCH3 as a driver of meningioma tumorigenesis and radiotherapy resistance, showing its role in tumor growth and survival in preclinical models.

bioRxiv · Jul 10, 2023 · PreprintCancer Biology

A Robust Deep Learning Approach for Joint Nuclei Detection and Cell Classification in Pan-Cancer Histology Images

V. Walia, S. Kotte, N. Sivadasan, H. Sharma, T. Joseph, B. Varma, G. Mukherjee, S. V.G

This paper introduces TransNuc, a deep learning model for detecting and classifying cell nuclei in histology images, showing improved performance across various cancer types.

bioRxiv · May 10, 2023 · PreprintPathology