Author

A. Bhaduri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 7 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 7 Research Focus:cell type annotation· 6 Research Focus:differential expression· 5 Assay:scRNA-seq· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2

Frequent Co-Authors

D. A. Nathanson· 3 shared P. R. Nano· 3 shared C. Tse· 2 shared D. J. Azizad· 2 shared D. R. Raleigh· 2 shared E. E. Crouch· 2 shared E. Fazzari· 2 shared H. A. Tum· 2 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

D. A. Nathanson

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

A neurovascular progenitor sits at the nexus of glioblastoma lineage trajectories

E. Fazzari, D. J. Azizad, K. Yu, W. Ge, M. X. Li, P. R. Nano, S. Baisiwala, A. Martija, R. L. Kan, J. Caston, L. N. Diafos, H. A. Tum, C. Tse, N. A. Bayley, V. Haka, , A. Bhaduri

This study identifies a neurovascular progenitor cell type in glioblastoma that links distinct malignant lineages and influences tumor composition and survival.

bioRxiv · Jul 24, 2024 · PreprintCancer Biology

Mixtures of Intrinsically Disordered Neuronal Protein Tau and Anionic Liposomes Reveal Distinct Anionic Liposome-Tau Complexes Coexisting with Tau Liquid-Liquid Phase Separated Coacervates

C. Tchounwou, A. J. Jobanputra, D. Lasher, B. J. Fletcher, J. Jacinto, A. Bhaduri, R. L. Best, W. S. Fisher, K. K. Ewert, Y. Li, S. C. Feinstein, C. R. Safinya

This paper investigates the interactions between tau protein and anionic liposomes, revealing distinct complexes and phase-separated coacervates under varying ionic conditions.

bioRxiv · Jul 15, 2024Biophysics

Radiation-Induced Cellular Plasticity: A Strategy for Combatting Glioblastoma

L. He, D. Azizad, K. Bhat, A. Ioannidis, C. J. Hoffman, E. Arambula, A. Bhaduri, H. I. Kornblum, F. Pajonk

This study shows that combining radiation with forskolin induces a differentiation-like state in glioma cells, reducing proliferation and extending survival in mouse models.

bioRxiv · May 13, 2024 · PreprintCancer Biology

Human Organoid Tumor Transplantation Identifies Functional Glioblastoma - Microenvironmental Communication Mediated by PTPRZ1

W. Ge, R. L. Kan, C. Yilgor, E. Fazzari, P. R. Nano, D. J. Azizad, M. Li, J. Y. Ito, C. Tse, H. A. Tum, J. Scholes, K. S. Patel, D. A. Nathanson, A. Bhaduri

The paper uses a human organoid tumor transplantation system to study glioblastoma-microenvironment interactions, identifying PTPRZ1 as a key mediator of intercellular communication.

bioRxiv · May 2, 2024 · PreprintCancer Biology

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

A. Choudhury, M. A. Cady, C.-H. G. Lucas, H. Najem, J. J. Phillips, B. Palikuqi, N. Zakimi, T. Joseph, J. O. Birreuta, W. C. Chen, N. A. O. Bush, S. L. Hervey-Jumper, O. D. Klein, C. M. Toedebusch, C. M. Horbinski, , D. R. Raleigh

This study identifies NOTCH3 as a driver of meningioma tumorigenesis and radiotherapy resistance, showing its role in tumor growth and survival in preclinical models.

bioRxiv · Jul 10, 2023 · PreprintCancer Biology

Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways

M. Pun, D. Pratt, P. R. Nano, P. K. Joshi, L. Jiang, B. Englinger, A. Rao, M. Cieslik, A. M. Chinnaiyan, K. Aldape, S. Pfister, M. Filbin, A. Bhaduri, S. Venneti

The paper identifies shared molecular features between H3K27M diffuse midline gliomas and PFA ependymomas, linking them to hindbrain developmental pathways.

bioRxiv · Nov 17, 2022Cancer Biology

Pathway-based approach reveals differential sensitivity of glioblastoma to E2F1 inhibition

A. G. Alvarado, K. Tessema, S. D. Muthukrishnan, M. Sober, R. Kawaguchi, A. Bhaduri, V. Swarup, D. A. Nathanson, S. A. Goldman, H. I. Kornblum

This study uses pathway analysis to identify E2F1 as a key driver of glioblastoma proliferation and shows its inhibition sensitizes tumors to radiation.

bioRxiv · Jun 19, 2021Cancer Biology

A draft single-cell atlas of human glioblastoma reveals a single axis of phenotype in tumor-propagating cells.

S. Muller, E. Di Lullo, A. Bhaduri, B. Alvarado, G. Yagnik, G. Kohanbash, M. Aghi, A. Diaz

This study constructs a single-cell atlas of human glioblastoma, revealing a single axis of variation in tumor-propagating cells and linking mesenchymal GSCs to poor prognosis.

bioRxiv · Jul 26, 2018 · PreprintCancer Biology