Author

C. M. Horbinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Ashworth· 1 shared A. B. Heimberger· 1 shared A. Bhaduri· 1 shared A. Choudhury· 1 shared A. J. Lauko· 1 shared A. Lo· 1 shared A. M. Khalil· 1 shared A. Perry· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Ashworth

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

A. Choudhury, M. A. Cady, C.-H. G. Lucas, H. Najem, J. J. Phillips, B. Palikuqi, N. Zakimi, T. Joseph, J. O. Birreuta, W. C. Chen, N. A. O. Bush, S. L. Hervey-Jumper, O. D. Klein, C. M. Toedebusch, C. M. Horbinski, , D. R. Raleigh

This study identifies NOTCH3 as a driver of meningioma tumorigenesis and radiotherapy resistance, showing its role in tumor growth and survival in preclinical models.

bioRxiv · Jul 10, 2023 · PreprintCancer Biology

A New Mouse Model of Diffuse Midline Glioma to Test Targeted Immunotherapies

M. D. Seblani, M. Zannikou, J. Duffy, R. N. Levine, Q. Liu, C. M. Horbinski, O. Becher, I. Balyasnikova

This paper develops a new mouse model of diffuse midline glioma to evaluate IL13R2-targeted immunotherapies, showing tumors with histopathological features of pediatric gliomas.

bioRxiv · Oct 15, 2021Cancer Biology

Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner

D. Bayik, Y. Zhou, C. Park, C. Hong, D. Vail, D. J. Silver, A. J. Lauko, G. A. Roversi, D. C. Watson, A. Lo, T. J. Alban, M. McGraw, M. D. Sorensen, M. M. Grabowski, B. Otvos, , J. Lathia

This study identifies sex-specific roles of MDSC subsets in glioblastoma, showing mMDSCs drive growth in males and gMDSCs in females, with potential therapeutic targets.

bioRxiv · Feb 19, 2020Immunology

Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma

T. Hasan, S. P. Caragher, J. M. Shireman, C. H. Park, F. Atashi, S. Baisiwala, G. Lee, D. Guo, M. Wu, J. Y. Wang, M. Dey, M. S. Lesniak, C. M. Horbinski, C. D. James, A. U. Ahmed

This study shows IL-8 promotes cellular plasticity and therapeutic resistance in glioblastoma by altering epigenetic marks and enhancing cancer initiating cell properties.

bioRxiv · Nov 16, 2018Cancer Biology