Author

C.-H. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Evolutionary Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2

Frequent Co-Authors

C.-C. Chen· 2 shared C.-w. Chen· 2 shared H. Ma· 2 shared J.-M. Yang· 2 shared R. P. Koche· 2 shared S. W. Lowe· 2 shared A. Banito· 1 shared A. D. Goldberg· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

C.-C. Chen

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Self-organizing glycolytic waves fuel cell migration and cancer progression

H. Zhan, D. S. Pal, J. Borleis, C. Janetopoulos, C.-H. Huang, P. N. Devreotes

The paper shows that glycolytic waves in the cell cortex drive migration and cancer progression by providing ATP for morphological events and correlating with metastatic potential.

bioRxiv · Jan 28, 2024Biochemistry

Targeting Ras signaling excitability in cancer cells through combined inhibition of FAK and PI3K

C.-C. Chen, S. Wang, J.-M. Yang, C.-H. Huang

This study shows that combining FAK and PI3K inhibitors synergistically suppresses cervical and pancreatic cancer cell growth by increasing apoptosis and reducing mitosis.

bioRxiv · Jun 12, 2023 · PreprintCancer Biology

MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

Y. M. Soto-Feliciano, C. Zhu, J. P. Morris, C.-h. Huang, R. P. Koche, Y.-j. Ho, A. Banito, C.-w. Chen, A. Shroff, S. Tian, L. Geulah, C.-c. Chen, M. Fennell, S. Armstrong, C. D. Allis, , S. W. Lowe

This study shows that MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer by affecting chromatin modifications and gene expression.

bioRxiv · Jun 7, 2022Cancer Biology

Phylogenomic analyses in the apple genus Malus s.l. reveal widespread hybridization and allopolyploidy driving the diversifications, with insights into the complex biogeographic history in the Northern Hemisphere

B.-B. Liu, C. Ren, M. Kwak, R. Hodel, C. Xu, J. He, W. Zhou, C.-H. Huang, H. Ma, D.-Y. Hong, G.-Z. Qian, J. Wen

bioRxiv · Oct 12, 2021 · PreprintEvolutionary Biology

Highly multiplexed imaging of biosensors in live cells

J.-M. Yang, W.-Y. Chi, J. Liang, P. A. Iglesias, C.-H. Huang

This paper develops barcoding proteins to enable highly multiplexed imaging of biosensors in live cells by computationally unmixing signals from different biosensors.

bioRxiv · Dec 11, 2020 · PreprintCell Biology

Analysis of paralogs in target enrichment data pinpoints multiple ancient polyploidy events in Alchemilla s.l. (Rosaceae)

D. F. Morales-Briones, B. Gehrke, C.-H. Huang, A. Liston, H. Ma, H. E. Marx, D. C. Tank, Y. Yang

The paper develops an automated orthology inference method to detect ancient polyploidy events in Alchemilla s.l. by analyzing paralogs in target enrichment data.

bioRxiv · Aug 21, 2020Evolutionary Biology

Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition

S. F. Cai, S. H. Chu, A. D. Goldberg, S. Parvin, R. P. Koche, J. L. Glass, E. M. Stein, M. S. Tallman, F. Sen, C. Famulare, M. Cusan, C.-H. Huang, C.-W. Chen, L. Zou, K. B. Cordner, , S. A. Armstrong

This study shows that leukemia cell of origin affects apoptotic priming and sensitivity to LSD1 inhibitors, with Evi1 modulating p53 stability and activity.

bioRxiv · May 11, 2020Cancer Biology