Author

Cameron Wehrfritz

Buck Institute for Research on Aging

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Birgit SchillingiD· 3 shared Joanna BonsiD· 3 shared Claudio A. HetziD· 2 shared Samah ShahiD· 2 shared Akos A. GerencseriD· 1 shared Alejandro Acevedo· 1 shared Alejandro Lopez‐RamireziD· 1 shared Anja N. HoltziD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Birgit SchillingORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Oral administration of dibenzoylmethane (DBM) prevents cognitive decline in a C9ORF72-mediated FTD mouse model

Paulina Torres, Daniela Becerra, José I. Astorga, Matías Fuentealba, Grant Kauwe, Luis Gonzalez, Guillermo Diaz, Vania Morales, Vicente Valenzuela, Cameron Wehrfritz, Yani Y. Ngwala, Claudia Sepúlveda-Quiñenao, Samah Shah, Joanna Bons, Leonard Petrucelli, , Claudio A. Hetz

This study shows that oral DBM treatment prevents cognitive decline in a C9ORF72 FTD mouse model without altering protein inclusions but corrects gene expression changes related to cytoskeleton, ALS, and metabolism.

bioRxiv · Aug 10, 2026 · PreprintMolecular Biology

Ketogenic diet administration later in life improves memory and regulates the synaptic cortical proteome through the cAMP/PKA signaling pathway in aging mice.

Diego Acuña-Catalán, Samah Shah, Cameron Wehrfritz, Mitsunori Nomura, Alejandro Acevedo, Cristina Olmos, Gabriel Quiroz, Hernán Huerta, Joanna Bons, Estíbaliz Ampuero, Úrsula Wyneken, Magdalena Sanhueza, Felipe Arancibia, Darwin Contreras, Julio César Cárdenas, , Christian Enrique González-Billault

This study shows that a short-term cyclic ketogenic diet improves memory and synaptic plasticity in aged mice by modulating the cAMP/PKA signaling pathway and cytoskeleton dynamics.

bioRxiv · Sep 7, 2023 · PreprintNeuroscience

Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

Kizito‐Tshitoko Tshilenge, Carlos Galicia Aguirre, Joanna Bons, Akos A. Gerencser, Nathan Basisty, Sicheng Song, Jacob Rose, Alejandro Lopez‐Ramirez, Swati B. Naphade, Ashley Loureiro, Elena Battistoni, Mateus Milani, Cameron Wehrfritz, Anja N. Holtz, Claudio A. Hetz, , Lisa Ellerby

The paper performs proteomic analysis of Huntington's disease patient-derived medium spiny neurons, identifying altered lipid metabolism and lipid droplet accumulation as key findings.

Molecular & Cellular Proteomics · Mar 22, 2023Peer-reviewedNeuroscience