Identification of Small Molecule Inhibitors of PPM1D Using a Novel Drug Discovery Platform
Subrata Shaw, Wei Jiang, Jason S. Rush, Nancy Dumont, John Kim, Ritu Singh, Adam P. Skepner, Carol Khodier, Cerise Raffier, Zachary Murphy, Ni Yan, Cameron Schluter, Yu Xiao, Mateusz Szuchnicki, Murugappan Sathappa, , Peter Grant Miller
This study identifies new PPM1D inhibitors using a drug discovery platform and shows their distinct biological effects compared to other DDR and p53 pathway modulators.
iScience · Feb 20, 2025Peer-reviewedCancer Biology