Author

Carolina Nör

Hospital for Sick Children

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Vijay RamaswamyiD· 2 shared Ahmed M. AmaniD· 1 shared Alexandria DeCarlo· 1 shared Algemir Lunardi BrunettoiD· 1 shared Alice Laschuk HerlingeriD· 1 shared Amarine Trolat· 1 shared Andre Tesainer BrunettoiD· 1 shared Brian L. GudenasiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Vijay RamaswamyORCID

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2 papers

Recent·Most cited

Cancer BiologyCell Reports MedicinePeer-reviewedJun 24, 2025

Targeting synthetic lethality between non-homologous end joining and radiation in very high-risk SHH medulloblastoma

Alexandria DeCarlo, Graham Dickson and Hugh MacLeod, Carolina Fernandes da Silva…·Vijay Ramaswamy

This study identifies DNA-PK as a synthetic lethal target in TP53-deficient SHH medulloblastoma, showing that inhibiting DNA-PK enhances radiosensitivity and improves survival in preclinical models.

6 citations

mousegenetic perturbation / CRISPR

𝕏 PostBluesky

Cancer BiologyCellsPeer-reviewedJan 7, 2025

Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma Neurospheres

Natália Hogetop Freire, Alice Laschuk Herlinger, Júlia Vanini…·Rafael Roesler

This study shows that valproic acid reduces medulloblastoma cell viability and affects stemness, differentiation, and gene expression through histone acetylation changes.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky