The Shu Complex Prevents Mutagenesis and Cytotoxicity of Single-Strand Specific Alkylation Lesions
Braulio Bonilla, Alexander J. Brown, Sarah R Hengel, Kyle Rapchak, Debra Mitchell, Catherine A. Pressimone, Adeola A Fagunloye, Thong Luong, Reagan A Russell, Rudri K Vyas, Tony M. Mertz, Hani S. Zaher, Nima Mosammaparast, Ewa P. Malc, Piotr A. Mieczkowski, , Kara Anne Bernstein
This study shows the yeast Shu complex prevents mutagenesis from 3meC lesions by binding to them and reducing replication errors.
eLife · Nov 1, 2021Peer-reviewedGenetics