Author

Debra Mitchell

Washington State UniversityORCID 0000-0002-9343-075XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 2 Organism:yeast· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Rudri K Vyas· 2 shared Steven A. RobertsiD· 2 shared Tony M. MertziD· 2 shared Adeola A FagunloyeiD· 1 shared Alexander J. BrowniD· 1 shared Anna J. WoodiD· 1 shared Braulio BonillaiD· 1 shared Cameron CorderoiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Rudri K Vyas

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genetic modifiers of APOBEC-induced mutagenesis

Tony M. Mertz, Elizabeth Rice-Reynolds, Ly Thi Huong Nguyen, Anna J. Wood, Cameron Cordero, Nicholas Bray, Victoria Harcy, Rudri K Vyas, Debra Mitchell, Kirill S. Lobachev, Steven A. Roberts

This paper identifies genetic modifiers of APOBEC-induced mutagenesis in yeast and human tumors, revealing factors that influence mutation patterns and DNA repair mechanisms.

Genome Research · Sep 1, 2023Peer-reviewedGenomics

The Shu Complex Prevents Mutagenesis and Cytotoxicity of Single-Strand Specific Alkylation Lesions

Braulio Bonilla, Alexander J. Brown, Sarah R Hengel, Kyle Rapchak, Debra Mitchell, Catherine A. Pressimone, Adeola A Fagunloye, Thong Luong, Reagan A Russell, Rudri K Vyas, Tony M. Mertz, Hani S. Zaher, Nima Mosammaparast, Ewa P. Malc, Piotr A. Mieczkowski, , Kara Anne Bernstein

This study shows the yeast Shu complex prevents mutagenesis from 3meC lesions by binding to them and reducing replication errors.

eLife · Nov 1, 2021Peer-reviewedGenetics