Author

Sarah R Hengel

Tufts UniversityORCID 0000-0002-0408-8623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:variant calling· 1 Organism:yeast· 1

Frequent Co-Authors

Kara Anne BernsteiniD· 2 shared Adeola A FagunloyeiD· 1 shared Alexander J. BrowniD· 1 shared Bennett Van HouteniD· 1 shared Braulio BonillaiD· 1 shared Catherine A. Pressimone· 1 shared Chelsea M. SmithiD· 1 shared Debra MitchelliD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Kara Anne BernsteinORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 21, 2024

The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA.

Sarah R Hengel, Katherine G. Oppenheimer, Chelsea M. Smith…·Kara Anne Bernstein

This study shows the Shu complex enhances RAD51 activity by stabilizing filaments and promoting RPA diffusion on ssDNA, with implications for cancer therapy.

14 citations

humanproteomics

𝕏 PostBluesky

GeneticseLifePeer-reviewedNov 1, 2021

The Shu Complex Prevents Mutagenesis and Cytotoxicity of Single-Strand Specific Alkylation Lesions

Braulio Bonilla, Alexander J. Brown, Sarah R Hengel…·Kara Anne Bernstein

This study shows the yeast Shu complex prevents mutagenesis from 3meC lesions by binding to them and reducing replication errors.

8 citations

yeastDNA methylation

𝕏 PostBluesky