Author

Chad C. Doucette

MaineHealth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Aaron Clifford BrowniD· 3 shared Devesh KesharwaniiD· 3 shared Clifford james RoseniD· 2 shared Lucy LiawiD· 2 shared Michele J. KarolakiD· 2 shared Su SuiD· 2 shared Victoria DeMambroiD· 2 shared Anne Harington· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCell Biology

Aaron Clifford BrownORCID

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Author profile →

3 papers

Recent·Most cited

Exosome Trafficking Is a Key Regulator of Adipocyte Thermogenesis

Devesh Kesharwani, Michele J. Karolak, Chad C. Doucette, Rachelle Mendola, Summer Pray, Raghu Bhardwaj, Su Su, Anne N. Harrington, Victoria DeMambro, Clifford james Rosen, Lucy Liaw, Aaron Clifford Brown

This study identifies exosome trafficking as a key regulator of beige adipocyte thermogenesis, showing that exosome release enhances thermogenic output and energy expenditure.

Proceedings of the National Academy of Sciences · Sep 8, 2026Peer-reviewedCell Biology

Quantifying Adipose Tissue Thermogenesis Using Highly Sensitive Isothermal Microcalorimetry

Pauke Carlijn Schots, Devesh Kesharwani, Chad C. Doucette, Aaron Clifford Brown

This study defines optimal conditions for measuring adipose tissue thermogenesis using isothermal microcalorimetry across different tissue types and handling conditions.

bioRxiv · Jan 8, 2026 · PreprintCell Biology

Isoform-Specific Control of Adipose Thermogenesis by the miR-27 Family Reveals Antagonism within a Polycistronic miRNA Cluster

Devesh Kesharwani, Michele J. Karolak, Chad C. Doucette, Eric R. Loomis, Sophia E Adami-Sampson, Su Su, Victoria DeMambro, Clifford james Rosen, Anne Harington, Larisa Ryzhova, Lucy Liaw, Aaron Clifford Brown

This study shows that miR-27a and miR-27b regulate adipose thermogenesis and metabolism, with their combined loss enhancing thermogenic activity and metabolic health.

bioRxiv · Jul 21, 2025 · PreprintPhysiology