Author

Chenyu Xu

Iowa State UniversityPrimary ORCID profile (0009-0006-4872-8174 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Chenyu XuiD1 paper · Nanjing University

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:graph neural network· 1

Frequent Co-Authors

Bin ZhangiD· 1 shared Chuanjiang Yang· 1 shared Die Hu· 1 shared Fangfang Huang· 1 shared Jin-Zhang ZengiD· 1 shared Jun WuiD· 1 shared Le JiniD· 1 shared Meizhi Jiang· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Bin ZhangORCID

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2 papers

Recent·Most cited

Homoharringtonine Promotes FTO Degradation to Suppress LILRB4-Mediated Immune Evasion in Acute Monocytic Leukemia

Fangfang Huang, Xiang Luo, Mengyu Zhang, Le Jin, Wenxin Sun, Peihan Chen, Xiuli Hong, Chenyu Xu, Meizhi Jiang, Die Hu, Bin Zhang, Shengwei Hu, Chuanjiang Yang, Rui Gao, Jin-Zhang Zeng, , Siming Chen

This study shows that homoharringtonine promotes FTO degradation, reducing LILRB4 expression and enhancing immune recognition in acute monocytic leukemia.

bioRxiv · Mar 15, 2025 · PreprintCancer Biology

scGAE: topology-preserving dimensionality reduction for single-cell RNA-seq data using graph autoencoder

Zixiang Luo, Chenyu Xu, Zhen Zhang, Wenfei Jin

scGAE is a dimensionality reduction method for scRNA-seq data that preserves topological structure, outperforming existing methods in trajectory reconstruction and clustering.

Scientific Reports · Oct 8, 2021Peer-reviewedBioinformatics