Author

Luis B Barreiro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1

Frequent Co-Authors

Anne Dumaine· 2 shared Vania YotovaiD· 2 shared Aaron J Sams· 1 shared Adnan AlaziziiD· 1 shared Allison L Richards· 1 shared Amy Mitrano· 1 shared Ariane Page Sabourin· 1 shared Athma A Pai· 1 shared

Activity by Year

2015-2016 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenomics

Anne Dumaine

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Widespread shortening of 3’ untranslated regions and increased exon inclusion are evolutionarily conserved features of innate immune responses to infection

Athma A Pai, Golshid Baharian, Ariane Page Sabourin, Jessica F Brinkworth, Yohann Nedelec, Joseph W Foley, Jean-Christophe Grenier, Katherine J Siddle, Anne Dumaine, Vania Yotova, Zachary P Johnson, Robert E Lanford, Christopher B Burge, Luis B Barreiro

The paper identifies widespread changes in RNA processing, including shorter 3’ UTRs and increased exon inclusion, in innate immune responses across humans and non-human primates.

PLOS Genetics · Sep 30, 2016Peer-reviewedGenomics

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.

Aaron J Sams, Anne Dumaine, Johann Nédélec, Vania Yotova, Caroline Alfieri, Jerome E Tanner, Philipp W Messer, Luis B Barreiro

The paper identifies a Neandertal haplotype at the OAS locus that affects innate immune responses by altering OAS gene expression and splice variants in humans.

bioRxiv · Sep 12, 2016Evolutionary Biology

Genetic and transcriptional analysis of human host response to healthy gut microbiome

Allison L Richards, Michael B Burns, Adnan Alazizi, Luis B Barreiro, Roger Pique-Regi, Ran Blekhman, Francesca Luca

This study identifies gene expression changes and host SNPs influenced by the gut microbiome in human cells, linking them to microbiome-related diseases.

mSystems · Aug 30, 2016Peer-reviewedGenomics

Mycobacterial infection induces a specific human innate immune response

John D Blischak, Ludovic Tailleux, Amy Mitrano, Luis B Barreiro, Yoav Gilad

The paper identifies genes specifically regulated by mycobacterial infection in macrophages, suggesting they may contribute to inter-individual susceptibility to tuberculosis.

Scientific Reports · Nov 20, 2015Peer-reviewedGenomics