Author

Sabrina Petri

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 5 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Organism:mouse· 6 Research Focus:differential expression· 5 Assay:electronic health records· 4 Research Focus:cell-cell communication· 3 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

Wayne N. FrankeliD· 6 shared David B. GoldsteiniD· 5 shared Michael J. BolandiD· 5 shared Sophie ColomboiD· 4 shared Daniel K. KrizayiD· 3 shared Jia Jie TeohiD· 3 shared Mu YangiD· 3 shared Andrew K. RessleriD· 2 shared

Activity by Year

2019-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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6 shared papersNeuroscience

Wayne N. FrankelORCID

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Author profile →

7 papers

Recent·Most cited

A transcriptional continuum links viral burden and host-cell biology in human lymphoid tissue

Jesse F. Mangold, Nadine Schrode, Trinisia Fortune, Aislinn M. Keane, Sanjana Shroff, Sabrina Petri, Benjamin C. Tweel, Kristin G. Beaumont, Talia H. Swartz

This study shows HIV transcription spans a continuum in human lymphoid tissue, linking viral burden to host-cell biology and suggesting persistent viral activity reflects a spectrum of host-virus states.

bioRxiv · Jul 11, 2026 · PreprintImmunology

Aberrant Local Synchrony in Distinct Mouse Models of Epileptic Encephalopathy

Andrew K. Ressler, Sarah A. Dugger, Sophie Colombo, Sabrina Petri, Daniel K. Krizay, Wayne N. Frankel, David B. Goldstein, Michael J. Boland

The paper develops topological synchrony measures to identify disease-relevant phenotypes in mouse models of epileptic encephalopathies using MEAs.

bioRxiv · Oct 24, 2023 · PreprintNeuroscience

Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency

Sarah A. Dugger, Ryan S. Dhindsa, Gabriela Louise de Almeida Sampaio, Andrew K. Ressler, Elizabeth E. Rafikian, Sabrina Petri, Verity A. Letts, Jia Jie Teoh, Junqiang Ye, Sophie Colombo, Mu Yang, Michael J. Boland, Wayne N. Frankel, David B. Goldstein

This study examines HNRNPU haploinsufficiency in mice, identifying neuroanatomical and transcriptomic changes, and highlights cell-type-specific gene expression dysregulation in excitatory neurons.

bioRxiv · May 1, 2020 · PreprintNeuroscience

The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity.

Amy N. Shore, Sophie Colombo, William F. Tobin, Sabrina Petri, Erin R. Cullen, Soledad Domínguez, Christopher D. Bostick, Michael A. Beaumont, Damian J. Williams, Dion Khodagholy, Mu Yang, Cathleen M. Lutz, Yueqing Peng, Jennifer N. Gelinas, David B. Goldstein, , Matthew C. Weston

The paper investigates how a gain-of-function K+ channel variant causes seizures by reducing inhibitory neuron excitability and increasing network hyperconnectivity.

bioRxiv · Mar 5, 2020 · PreprintNeuroscience

Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors

Jia Jie Teoh, Narayan Subramanian, Maria Elena Pero, Francesca Bartolini, Ariadna Amador, Ayla Kanber, Damian J. Williams, Sabrina Petri, Mu Yang, Andrew S. Allen, Jules C. Beal, Sheryl R. Haut, Wayne N. Frankel

This study shows that Arfgef1 haploinsufficiency in mice reduces dendritic surface GABAAR and alters endosome composition, leading to increased seizure susceptibility.

Neurobiology of Disease · Nov 2, 2019Peer-reviewedGenetics

Modeling and treating GRIN2A developmental and epileptic encephalopathy in mice

Ariadna Amador, Christopher D. Bostick, Heather E. Olson, Jurrian Peters, Chad R. Camp, Daniel K. Krizay, Wenjuan Chen, Wei Han, Weiting Tang, Ayla Kanber, Sukhan Kim, Jia Jie Teoh, Sabrina Petri, Hunki Paek, Ana Kim, , Wayne N. Frankel

This study models GRIN2A-related DEE in mice, identifies seizure and behavioral abnormalities, and evaluates treatment strategies.

bioRxiv · Aug 16, 2019 · PreprintNeuroscience

G protein-coupled potassium channels implicated in mouse and cellular models of GNB1 Encephalopathy

Sophie Colombo, Sabrina Petri, Boris Shalomov, Haritha P. Reddy, Galit Tabak, Ryan S. Dhindsa, Sahar Gelfman, Sasa Teng, Daniel K. Krizay, Elizabeth E. Rafikian, Amal Kanti Bera, Mu Yang, Michael J. Boland, Yueqing Peng, Wayne N. Frankel, , David B. Goldstein

This study identifies GNB1 mutations causing neurodevelopmental disorder and shows ethosuximide effectively treats symptoms in mouse and cellular models.

bioRxiv · Jul 9, 2019 · PreprintNeuroscience