Author

Christopher Lloyd

Indiana University School of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adrian L. OblakiD· 1 shared Alaina M. ReaganiD· 1 shared Alan KennedyiD· 1 shared Amanda A. Bedwell· 1 shared Andy Po‐Yi TsaiiD· 1 shared Bridget M Perkins· 1 shared Bruce T. LambiD· 1 shared Carolina T OrozcoiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Adrian L. OblakORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80 / PD-L1 interaction

Maximillian A Robinson, Alan Kennedy, Carolina T Orozco, Hung-Chang Chen, E. A. Waters, Dalisay Giovacchini, Kay Yeung, Lily Filer, Claudia Hinze, Christopher Lloyd, Simon J Dovedi, David M Sansom

This paper shows that rigid, bivalent CTLA-4 binding to CD80 disrupts the cis CD80/PD-L1 interaction, promoting PD-L1 availability through orientation and cross-linking.

bioRxiv · Apr 19, 2024 · PreprintImmunology

Plcg2M28L interacts with high fat-high sugar diet to accelerate Alzheimers disease-relevant phenotypes in mice

Adrian L. Oblak, Kevin P. Kotredes, Ravi S. Pandey, Alaina M. Reagan, Cynthia M. Ingraham, Bridget M Perkins, Christopher Lloyd, Deborah Baker, Peter Bor‐Chian Lin, Disha M. Soni, Andy Po‐Yi Tsai, Scott A. Persohn, Amanda A. Bedwell, Kierra Eldridge, Rachael Speedy, , Gareth R. Howell

This study shows that a high fat-high sugar diet interacts with the Plcg2M28L genetic variant to accelerate Alzheimer's disease-like phenotypes in mice.

Frontiers in Aging Neuroscience · Jun 24, 2022Peer-reviewedNeuroscience