A Spray Dried Replicon Vaccine Platform for Pandemic Response
Wynton D. McClary, John Z. Chen, Hui Wang, Ethan Lo, Julie Bakken, Joseph McCollum, Christopher Press, Eduard H. Melief, Devin S. Brandt, Andrew R. Martin, Reinhard Vehring, Darshan N. Kasal, Emily A. Voigt, Alana Gerhardt
This paper demonstrates the successful spray drying of a replicon-NLC vaccine against H5N1 avian influenza, maintaining stability and immunogenicity for up to 3 months at 4°C.
International Journal of Pharmaceutics · May 26, 2025Peer-reviewedImmunology