Author

Pauline Fusco

Access to Advanced Health Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Research Focus:host-pathogen & immune response· 3 Organism:rat· 3 Research Focus:benchmarking· 1 Organism:multiple species· 1

Frequent Co-Authors

Darshan N. KasaliD· 4 shared Emily A. VoigtiD· 4 shared Jasneet Singh· 4 shared Julie Bakken· 4 shared Madeleine F. JenneweiniD· 4 shared Alana GerhardtiD· 3 shared Corey CasperiD· 3 shared Matthew YkemaiD· 3 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Darshan N. KasalORCID

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4 papers

Recent·Most cited

The ID93 + GLA-3M-052-LS vaccine candidate elicits mucosal and systemic immunogenicity and protective efficacy against Mycobacterium tuberculosis challenge in BCG-primed Collaborative Cross inbred mice

Emily A. Voigt, Anas Alsharaydeh, Darshan N. Kasal, Madeleine F. Jennewein, Devin S. Brandt, Susan Xiaoqin Lin, Jasneet Singh, Julie Bakken, Raodoh Mohamath, Pauline Fusco, Jordi Bertran Torrelles, Gillian Beamer, Christopher B. Fox

This study evaluates a TB vaccine candidate, ID93 + GLA-3M-052-LS, showing enhanced mucosal and systemic immunity and protection against Mtb in BCG-primed mice.

bioRxiv · Oct 31, 2025 · PreprintImmunology

A bivalent self-amplifying RNA vaccine against yellow fever and Zika viruses

Peter Battisti, Matthew Ykema, Darshan N. Kasal, Madeleine F. Jennewein, Samuel Beaver, Abbie E. Weight, Derek Hanson, Jasneet Singh, Julie Bakken, Noah Cross, Pauline Fusco, Jacob F. Archer, Sierra Reed, Alana Gerhardt, Justin G. Julander, , Emily A. Voigt

This paper develops a bivalent self-amplifying RNA vaccine against yellow fever and Zika viruses, showing it induces robust immune responses and complete protection in animal models.

Frontiers in Immunology · Apr 29, 2025Peer-reviewedImmunology

Development of an Intranasally- and Intramuscularly-Administrable Replicon Vaccine Efficacious Against H5N1 Influenza Virus

Wynton D. McClary, Devin S. Brandt, Madeleine F. Jennewein, Jasneet Singh, Samuel Beaver, Matthew Ykema, Christopher Press, Eduard H. Melief, Julie Bakken, Pauline Fusco, Ethan Lo, Peter Battisti, Noah Cross, Darshan N. Kasal, Airn E. Hartwig, , Emily A. Voigt

This paper develops a replicon vaccine against H5N1 influenza that can be administered intranasally or intramuscularly, showing efficacy in reducing morbidity and mortality in a ferret model.

bioRxiv · Mar 31, 2025 · PreprintImmunology

An intranasal, NLC-delivered self-amplifying RNA vaccine establishes protective immunity against pre-pandemic H5N1 and H7N9 influenza

Matthew Ykema, Michael A. Davis, Darshan N. Kasal, Madeleine F. Jennewein, Eric Yu Wei Lo, Jasneet Singh, Samuel Beaver, Noah Cross, Eduard H. Melief, Sierra Reed, Christopher Press, Pauline Fusco, Julie Bakken, Corey Casper, Airn E. Hartwig, , Emily A. Voigt

An intranasal self-amplifying RNA vaccine delivered via nanostructured lipid carriers induces mucosal immunity and protects against H5N1 and H7N9 influenza in ferrets.

bioRxiv · Jan 7, 2025 · PreprintImmunology