Author

Christopher W. Wright

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Aditya ShethiD· 1 shared Amber L. SmithiD· 1 shared Gautam PareekiD· 1 shared Geoffrey A. M. NealeiD· 1 shared Hailey S RossiD· 1 shared Huiyun WuiD· 1 shared Jingjun LüiD· 1 shared John D. SchuetziD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aditya ShethORCID

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1 paper

Recent·Most cited

Somatic mtDNA Mutation Burden Shapes Metabolic Plasticity in Leukemogenesis

Xiujie Li-Harms, Jingjun Lü, Yu Fukuda, John Lynch, Aditya Sheth, Gautam Pareek, Marcin M. Kamiński, Hailey S Ross, Christopher W. Wright, Amber L. Smith, Huiyun Wu, Yong‐Dong Wang, Marc B. Valentine, Geoffrey A. M. Neale, Peter Vogel, , Mondira Kundu

This study shows that somatic mtDNA mutations affect metabolic plasticity in leukemia development, with heterozygous mutations supporting NMyc-driven leukemia while homozygous mutations impair it.

Science Advances · Jan 1, 2025Peer-reviewedCancer Biology