Author

Chung-Fan Kuo

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Oluwatobi Helen Babayemi· 3 shared Rachael W. SirianniiD· 3 shared Hong Wei YangiD· 2 shared Kha Uyen Dam· 2 shared Shaokuan Zheng· 2 shared Constance Jennifer Mietus· 1 shared David I. SandbergiD· 1 shared Elena A. Andreyko· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

Oluwatobi Helen Babayemi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ang2 and TAT targeting of leptomeningeal disease by the intravenous and intrathecal routes: a comparative analysis

Chung-Fan Kuo, Oluwatobi Helen Babayemi, Kha Uyen Dam, Shaokuan Zheng, Hong Wei Yang, Rachael W. Sirianni

This study compares the targeting efficiency of Ang2 and TAT peptides via intravenous and intrathecal routes in leptomeningeal disease models, finding TAT achieves better targeting in specific regions.

bioRxiv · Aug 29, 2026 · PreprintBioengineering

Intrathecal infusion of hypertonic fluid enables CSF Flow Enhancement (CFE) to facilitate nanoparticle delivery to the brain and spinal cord

Oluwatobi Helen Babayemi, Kha Uyen Dam, Chung-Fan Kuo, Olivia Mihalek, Elena A. Andreyko, Constance Jennifer Mietus, Shaokuan Zheng, Hong Wei Yang, Rachael W. Sirianni

This study demonstrates that intrathecal infusion of hypertonic fluid enhances cerebrospinal fluid flow, significantly improving nanoparticle delivery to the central nervous system.

bioRxiv · Jul 1, 2026 · PreprintBioengineering

Nanoparticle encapsulation enhances spatial distribution of Panobinostat to treat metastatic medulloblastoma via the intrathecal route

Oluwatobi Helen Babayemi, Jon D. Larson, Sauradip Chaudhuri, Fred Valesquez, Janelle Morton, Chung-Fan Kuo, Lindsey K. Sablatura, Gerard Baquer, Michael S Reagan, Sylwia A. Stopka, David I. Sandberg, Nathalie Y.R. Agar, Eva Marie Sevick-Muraca, Robert J. Wechsler‐Reya, Rachael W. Sirianni

This study develops a nanoparticle system to deliver Panobinostat intrathecally for treating metastatic medulloblastoma, showing improved drug distribution and survival benefits in mice.

bioRxiv · Apr 2, 2026 · PreprintBioengineering