Author

Claire M O'Brien

The Wistar Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander M. PriceiD· 1 shared Alison YuiD· 1 shared Clayton J. OtteriD· 1 shared Daniel T. ClaiborneiD· 1 shared Lorenzo SerraiD· 1 shared Molly R. PattersoniD· 1 shared Reyes Acosta· 1 shared Susan Reich WeissiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Alexander M. PriceORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintJun 27, 2026

Inhibition of RNA splicing is a novel therapeutic strategy for disruption of nuclear replicating viruses

Lorenzo Serra, Claire M O'Brien, Molly R. Patterson…·Alexander M. Price

This study shows that inhibiting RNA splicing reduces viral replication in splicing-dependent viruses like adenovirus, HSV-1, and influenza A, suggesting a new antiviral strategy.

DOI 10.64898/2026.06.26.734849

humanbulk RNA-seq

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