Author

Reyes Acosta

Altius Institute for Biomedical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander Joel FederationiD· 1 shared Alexander M. PriceiD· 1 shared Alison YuiD· 1 shared Alister P. W. FunnelliD· 1 shared Benjamin P. Van Biber· 1 shared Christie CiarloiD· 1 shared Claire M O'Brien· 1 shared Clayton J. OtteriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSynthetic Biology

Alexander Joel FederationORCID

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2 papers

Recent·Most cited

Inhibition of RNA splicing is a novel therapeutic strategy for disruption of nuclear replicating viruses

Lorenzo Serra, Claire M O'Brien, Molly R. Patterson, Clayton J. Otter, Alison Yu, Reyes Acosta, Daniel T. Claiborne, Susan Reich Weiss, Alexander M. Price

This study shows that inhibiting RNA splicing reduces viral replication in splicing-dependent viruses like adenovirus, HSV-1, and influenza A, suggesting a new antiviral strategy.

bioRxiv · Jun 27, 2026 · PreprintMicrobiology

Quantitative dialing of gene expression via precision targeting of KRAB repressor

Matthew S. Wilken, Christie Ciarlo, Jocelynn R. Pearl, Elaine V. Schanzer, Hanna Liao, Benjamin P. Van Biber, Konstantin Queitsch, Jordan E. Bloom, Alexander Joel Federation, Reyes Acosta, Shinny Vong, Ericka Otterman, Douglas Dunn, Hao Wang, Pavel Zrazhevskiy, , John A. Stamatoyannopoulos

This study demonstrates precise control of gene expression levels by targeting the KRAB repressor domain in human cells.

bioRxiv · Feb 19, 2020 · PreprintSynthetic Biology