Author

Claudia Misiak

Martin Luther University Halle-Wittenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alice WedleriD· 3 shared Stefan HüttelmaieriD· 3 shared Andrea SinziD· 2 shared Christian H. IhlingiD· 2 shared Danny MisiakiD· 2 shared Khursheed Ul Islam MiriD· 2 shared Markus GlaßiD· 2 shared Nadine BleyiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Alice WedlerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting IGF2BP1 Creates a Mitotic Vulnerability in Colorectal Carcinoma

Bruno Griesler, Sven Hagemann, Robert E. Winkler, Alice Wedler, Claudia Misiak, Danny Misiak, Alexander Rausch, Jana Lützkendorf, Thomas Mueller, Khursheed Ul Islam Mir, Christian H. Ihling, Florian Wolfgang Otto, Andrea Sinz, Jan‐Henning Klusmann, Michael Heuser, , Stefan Hüttelmaier

This study identifies IGF2BP1 as a regulator of mitotic integrity in CRC, showing that its inhibition creates a therapeutic vulnerability that synergizes with paclitaxel.

bioRxiv · Oct 26, 2026 · PreprintCancer Biology

RNA-seq derived sequence variations are excellent features for cell line identification

Lisa Müller, Simon Müller, Khursheed Ul Islam Mir, Jana Lange, Sven Hagemann, Alice Wedler, Frank Hause, Claudia Misiak, Danny Misiak, Tony Gutschner, Stefan Hüttelmaier, Markus Glaß

This study shows RNA-seq-derived sequence variations can reliably identify cell lines and detect cross-contamination using machine learning.

Computational and Structural Biotechnology Journal · Jan 1, 2025Peer-reviewedGenomics

RAVER1 interconnects lethal EMT and miR/RISC activity by the control of alternative splicing

Alice Wedler, Nadine Bley, Markus Glaß, Simon Müller, Laura Schian, Kingsley Benjamin Obika, Marcell Lederer, Claudia Misiak, Tommy Fuchs, Marcel Köhn, Roland Jacob, Tony Gutschner, Christian H. Ihling, Andrea Sinz, Stefan Hüttelmaier

This paper investigates RAVER1's role in controlling alternative splicing and its impact on miR/RISC activity and EMT in cancer cells.

bioRxiv · Jun 14, 2023 · PreprintMolecular Biology