Author

Bruno Griesler

Martin Luther University Halle-Wittenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Jan‐Henning KlusmanniD· 2 shared Robert E. WinkleriD· 2 shared Stefan HüttelmaieriD· 2 shared Alexander Rausch· 1 shared Alice WedleriD· 1 shared Andrea SinziD· 1 shared Christian H. IhlingiD· 1 shared Claudia Misiak· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Jan‐Henning KlusmannORCID

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2 papers

Recent·Most cited

Targeting IGF2BP1 Creates a Mitotic Vulnerability in Colorectal Carcinoma

Bruno Griesler, Sven Hagemann, Robert E. Winkler, Alice Wedler, Claudia Misiak, Danny Misiak, Alexander Rausch, Jana Lützkendorf, Thomas Mueller, Khursheed Ul Islam Mir, Christian H. Ihling, Florian Wolfgang Otto, Andrea Sinz, Jan‐Henning Klusmann, Michael Heuser, , Stefan Hüttelmaier

This study identifies IGF2BP1 as a regulator of mitotic integrity in CRC, showing that its inhibition creates a therapeutic vulnerability that synergizes with paclitaxel.

bioRxiv · Oct 26, 2026 · PreprintCancer Biology

Lineage-restricted dependency on an oncofetal SNHG29-IGF2BP1 RNA axis in acute megakaryoblastic leukemia

Robert E. Winkler, Bruno Griesler, Wolfgang Sippl, Reinier Abraham Boon, Stefanie Dimmeler, Ilka Wittig, Marie‐Laure Yaspo, Stefan Hüttelmaier, Raj Bhayadia, Dirk Heckl, Jan‐Henning Klusmann

This study identifies SNHG29 and IGF2BP1 as a lineage-specific oncogenic circuit in AMKL, showing their dependency and therapeutic vulnerability.

Leukemia · Jun 30, 2026Peer-reviewedCancer Biology