De novo design of protein minibinder agonists of TLR3
Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King
This study designs protein minibinders that act as agonists for TLR3, showing nanomolar binding and biological activity in cell lines.
bioRxiv · Apr 17, 2024Biochemistry